Dosage, safety, and side effects

Dosage, safety, and side effects

There is conflicting information regarding the safety of noni juice, as only a few human studies have evaluated its dosage and side effects.

For example, one small study in healthy adults indicated that drinking up to 25 ounces (750 ml) of noni juice per day is safe (33Trusted Source).

However, in 2005, a few cases of liver toxicity were reported in people consuming noni juice. The European Food Safety Authority (EFSA) then re-evaluated the fruit, concluding that noni juice alone did not cause these effects (34Trusted Source, 35Trusted Source, 36).

In 2009, EFSA issued another statement confirming the safety of noni juice for the general population. However, EFSA experts did report that some individuals may have a particular sensitivity for liver toxicity effects (37).

In addition, people with chronic kidney disease or kidney failure may want to avoid noni juice — as it’s high in potassium and may lead to unsafe levels of this compound in the blood (38Trusted Source).

Additionally, noni juice may interact with certain medications, such as those used to treat high blood pressure or those used to slow blood clotting. For this reason, it is important to consult with your medical provider before drinking noni juice.

High in sugar
Noni juice may contain high amounts of sugar due to the variability between brands. What’s more, it’s mixed with other fruit juices that are often very sweet.

In fact, 3.5 ounces (100 ml) of noni juice contains roughly 8 grams of sugar. Studies show that sugar-sweetened beverages like noni juice may increase your risk of metabolic diseases, such as nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (39, 40Trusted Source, 41Trusted Source).

Thus, it may be best to drink noni juice in moderation — or avoid it if you limit your sugar intake.

SUMMARY
Noni juice is likely safe to drink for the general population. However, people with kidney problems and who take certain medications may wish to avoid noni juice. It can also be high in sugar.

The bottom line
Noni juice is derived from a Southeast Asian fruit.

It’s particularly rich in vitamin C and may offer anti-inflammatory and antioxidant benefits — such as pain relief and improved immune health and exercise endurance. However, more research is needed.

Keep in mind that commercial varieties are often mixed with other juices and may be packed with sugar.

It’s also important to remember that — despite exhibiting some benefits for smokers — noni juice should not be considered a preventative measure for tobacco-related illnesses or a replacement for quitting.

Overall, noni juice is likely safe. However, you may want to check with your medical provider if you’re taking certain medications or have kidney problems.

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